Huanbiao Mo

PhD, Nutritional Sciences, University of Wisconsin-Madison

MS, Plant Physiology, Shanghai Institute of Plant Physiology, Chinese Academy of Sciences

BS, Biochemistry, Fudan University

Selected Publications

Journal articles

1. Ji X, Yao H, Meister ML, Gardenhire DS, Mo H. (in press) Tocotrienols: dietary supplement for chronic obstructive pulmonary disease. Antioxidants.
2. Shen CL, Ramamoorthy S, Kaur G, Dufour JM, Wang R, Mo H, Watkins BA. (2021) Dietary annatto-extracted tocotrienol reduces inflammation and oxidative stress and improves macronutrient metabolism in obese mice: a metabolic profiling study. Nutrients. 13:1267. Doi: 10.3390/nu13041267.
3. Chan D, Meister ML, Madhani CR, Elfakhani M, Yount ST, Ji X, Feresin RG, Wanders D, Mo H. (2020) Synergistic impact of xanthorrhizol and d-δ-tocotrienol on the proliferation of murine B16 melanoma cells and human DU145 prostate carcinoma cells. Nutrition & Cancer. PMID: 32811212. doi: 10.1080/01635581.2020.1807573.
4. Meister ML, Mo H, Ji X, Shen CL. (2020) Tocotrienols in bone protection: evidence from preclinical studies. eFood. 1:217-25. doi: 10.2991/efood.k.200427.001.
5. Mo H, Jeter R, Backmann A, Yount ST, Shen CL, Yeganehjoo H. (2019) The potential of isoprenoids in adjuvant cancer therapy to reduce adverse effects of statins. Frontiers in Pharmacology. doi: 10.3389/fphar.2018.01515.
6. Shen CL, Wang S, Yang S, Tomison MD, Abbasi M, Hao L, Scott S, Khan MS, Romero AW, Felton CK, Mo H. (2018) A 12-week evaluation of annatto tocotrienol supplementation for postmenopausal women: safety, quality of life, body composition, physical activity, and nutrient intake.BMC Complementary and Alternative Medicine. 18:198. PMID: 29954374. PMCID: PMC6022510. doi: 10.1186/s12906-018-2263-0.
7. Shen CL, Kaur G, Wanders D, Sharma S, Tomison M, Ramalingam L, Chung E, Moustaid-Moussa N, Mo H, Dufour J. (2018) Annatto-extracted tocotrienols improve glucose homeostasis and bone properties in high-fat diet-induced type II diabetic mice by decreasing the inflammatory response. Scientific Reports. 8:11377. PMID: 30054493. PMCID: PMC6063954. doi: 10.1038/s41598-018-29063-9.
8. Shen CL, Yang S, Tomison MD, Romero AW, Felton CK, Mo H. (2018) Tocotrienols supplementation suppressed bone resorption and oxidative stress in postmenopausal osteopenic women: a 12-week randomized double-blinded placebo-controlled trial. Osteoporosis International. 29:881-91. PMID: 29330573. doi: 10.1007/s00198-017-4356-x.
9. Chung E, Mo H, Wang S, Zu Y, Elfakhani M, Rios SR, Chyu MC, Yang RS, Shen CL. (2018) Potential roles of vitamin E in age-related changes in skeletal muscle health. Nutrition Research. 49:23-6. PMID: 29420990. doi: 10.1016/j.nutres.2017.09.005.
10. Shen CL, Klein A, Chin KY, Mo H, Tsai P, Yang RS, Chyu MC, Ima-Nirwana S. (2017) Tocotrienols for bone health: a translational approach.Annals of the New York Academy of Sciences. 1401:150-65. PMID: 28891093. doi: 10.1111/nyas.13449.
11. Yeganehjoo H, DeBose-Boyd R, McFarlin BK, Mo H. (2017) Synergistic impact of d-δ-tocotrienol and geranylgeraniol on the growth and HMG CoA reductase of human DU145 prostate carcinoma cells. Nutrition and Cancer. 69:682-91. PMID 28362175. doi: 10.1080/01635581.2017.1299876.
12. Chen L, Mo H, Zhao L, Gao W, Wang S, Cromie MM, Lu C, Wang JS, Shen CL. (2017) Therapeutic properties of green tea against environmental insults. Journal of Nutritional Biochemistry. 40:1-13. PMID 27723473. PMCID: PMC5124528. doi: 10.1016/j.jnutbio.2016.05.005.
13. Torabi S, Yeganehjoo H, Shen CL, Mo H. (2016) PPARγ downregulation mediates the inhibitory effect of d-δ-tocotrienol on the differentiation of murine 3T3-F442A preadipocytes. Nutrition Research. PMID 27884413; doi: 10.1016/j.nutres.2016.11.001.
14. Shen CL, Mo H, Yang S, Wang S, Felton CK, Tomison MD, Soelaiman IN. (2016) Safety and efficacy of tocotrienol supplementation for bone health in postmenopausal women: protocol for a dose-response double-blinded placebo-controlled randomized trial. BMJ Open. 6:e012572. PMID 28011809. doi: 10.1136/bmjopen-2016-012572.
15. Torabi S, Mo H. (2016) trans, trans-Farnesol as a mevalonate-derived inducer of murine 3T3-F442A preadipocyte differentiation. Experimental Biology and Medicine (Maywood). 241:493-500. PMID: 26660152. doi: 10.1177/1535370215620855.
16. Cao HH, Chu JH, Kwan HY, Su T, Yu H, Cheng BCY, Fu X, Guo H, Li T, Tse AKW, Chou GX, Mo H, Yu ZL. (2016) Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma. Scientific Reports. PMID 26911838. PMCID: PMC4766576. doi: 10.1038/srep21731.
17. Xia W, Mo H. (2016) Potential of tocotrienols in the prevention and therapy of Alzheimer’s disease. Journal of Nutritional Biochemistry 31:1-9. PMID 27133418.

Book chapters

1. Shen CL, Zhang, J, Mo H, Chyu MC, Tang L, Wang JS. (in press) Green tea catechins and tocotrienols in bone protection: evidence from preclinical studies, in Natural Products and Remedies: Evidence based evaluation for use in human disease prevention and treatment. Ed S.S. Prabhakar. Springer Nature publisher.

Selected Invited Lectures/Oral Presentations

Functional foods and Alzheimer’s disease. The 1^st Wenzhou Medical University Nursing International Summit: The Role of Nursing in Human Development, Wenzhou, China, 2017.

Mechanisms for vitamin E and Alzheimer’s disease. The 10^th Special Nutrition Conference of Chinese Nutrition Society, Wenzhou, China, 2017.

Are all vitamin E equal? The 13^th China Nutrition Science Congress, Beijing, China, 2017.

Tocotrienol and the mevalonate pathway in adipogenesis. Hong Kong Baptist University, 2017.

Tocotrienol and adipogenesis: role of the mevalonate pathway. The 4^th Guangzhou International Symposium for Nutrition and Health and the 2016 Annual Conference of Geriatric Nutrition Branch of Chinese Nutrition Society, Guangzhou, China, 2016.

Exploration of tocotrienols for the prevention of Alzheimer’s disease. Chinese Congress on Gerontology and Health Industry, Suzhou, China, 2016.

Mevalonate pathway in cancer and adipogenesis. Center for Diagnostics and Therapeutics, Georgia State University, 2016.

Patents

Elson CE, Mo H. Acyclic monoterpenoid derivatives. US patent 6,303,654.

Elson CE, Jung M, Mo H. Acyclic isoprenoid ether derivatives as chemotherapeutics. US patent 6,566,397.

Mo H, Elson CE, Peffley DM, Hentosh PM. Composition and method for treating cancer. US patent 7,074,825.

Memberships

2013-present
Co-Chair, China Interest Group, American Society for Nutrition

2016-present
Member, Gerontological Society of America

2001-present
Member, American Society for Nutrition

2017-present
Associate Editor, Nutrition & Metabolism